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Treatment of internal contamination
Main chelating agents recommended* for decorporation
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Compartmental Absorption |
Chelating agents |
Elements |
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Whole body |
Water (dilution) |
3H* |
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Intestine |
AI-phosphate
Mg-Ba-sulphate, ammonium chloride
Prussian Blue: Fe4[Fe(CN)6]3
Gluconates, Alginates
Penicillamine, trientine |
P*, Ca, Sr*, Ba, Sb*, Hg*, Zr*, Cr*,
Act*, U*
Ca*, Sr*, Ba*, Ra*, Act*, Po*
Cs*, TI, Rb
Ba*, Ca*, Sr*, Co*
Cu, Co, Po |
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Lung |
DTPA aerosol |
Actinides : Th, U, Pu, Am, Cm |
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Thyroid |
Potassium iodine (KI) |
I* |
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Blood |
DTPA-(Ca/Zn)
Siderophores (LIHOPO...)
BAL: dimercaprol (thiol : -SH)
DMSA: dimercaptosuccinic acid
DMSP: dimercaptosulfonic acid
Prussian Blue: Fe4[Fe(CN)6]3
Sodium bicarbonate, phosphonates |
Act : Th*, Pu*, Am*, Cm*, Co*, Zr,
Ni, Ru* , Cr*
Po*, Sb*, Au*, As*, Hg*, Ni*
Po, Sb, Au, As, Hg, Ni
Po, Sb, Au, As, Hg, Ni
Cs*, TI*
U* |
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* National medical guidebook for radiological events (ASN, 2008)
* Guidance for infernal radioactive contamination (US HHS dept, FDA, 2006) |
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