DACTARI : DAtabase for Chemical Toxicity and radiotoxicity Assessment of RadIonuclides

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Treatment of internal contamination

Main chelating agents recommended* for decorporation

Compartmental Absorption Chelating agents Elements
Whole body Water (dilution) 3H*
Intestine AI-phosphate

Mg-Ba-sulphate, ammonium chloride
Prussian Blue: Fe4[Fe(CN)6]3
Gluconates, Alginates

Penicillamine, trientine
P*, Ca, Sr*, Ba, Sb*, Hg*, Zr*, Cr*,
Act*, U*
Ca*, Sr*, Ba*, Ra*, Act*, Po*
Cs*, TI, Rb
Ba*, Ca*, Sr*, Co*
Cu, Co, Po
 
Lung DTPA aerosol Actinides : Th, U, Pu, Am, Cm
Thyroid Potassium iodine (KI) I*
Blood DTPA-(Ca/Zn)
Siderophores (LIHOPO...)
BAL: dimercaprol (thiol : -SH)
DMSA: dimercaptosuccinic acid
DMSP: dimercaptosulfonic acid

Prussian Blue: Fe4[Fe(CN)6]3
Sodium bicarbonate
, phosphonates
Act : Th*, Pu*, Am*, Cm*, Co*, Zr,
Ni, Ru* ,  Cr*
Po*, Sb*, Au*, As*, Hg*, Ni*
Po, Sb, Au, As, Hg, Ni
Po, Sb, Au, As, Hg, Ni
Cs*, TI*
U*
 
* National medical guidebook for radiological events (ASN, 2008)
* Guidance for infernal radioactive contamination (US HHS dept, FDA, 2006)

 




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